SENALAX

SENALAX

Average: 3.7 (3 votes)

•    Laxative
•    Purgative

Producing country: 
Iran
Pharmaceutical form: 
Tablet
Indications: 
Laxative, Purgative
Administration and Dosage: 
  • As Laxative:

o    Children 6-12 years: 1 tablet daily.
o    Adults: 1-2 tablets daily.

  •  As purgative: 

o    Children 6-12 years: 2 tablets daily.
o     Adults 2-4 tablets daily.
    It is recommended to be Consumed along with 6-8 glasses of water before bed.
 

Technical Specifications: 
  • This product is made from high quality local and imported herbs organically planted and ‎harvested. It has been formulated by ‎Iran Darouk Pharmaceuticals.
Expiry date: 
3 Years
Drug interactions: 
  • This product changes urine color and increases urinary pH, may interact with diagnostic laboratory tests (such as measurement of urine urobilinogen and estrogen measurement by Cooper method).
  • Products containing Senna interact with blood potassium lowering drugs such as thiazide diuretics, adrenocorticosteroids, licorice root, cardiac glycosides, antiarrhythmic drugs, and possibly cause cardiac and nerve-muscle disorders.
  • SenaLax prevents estrogen absorption and decreases its serum level.
  • Indomethacin and nifedipine decrease therapeutic effects of SenaLax.
Physical characteristics: 
30 tablets, blister pack in a cardboard box.
25 tablets inside the PE bottle.
Storage: 
  • Store in a dry place, keep away from direct sunlight and below 30°C.
Contraindications and precautions: 
  • Children below 6 years, Intestinal obstruction, unknown rectal bleeding, inflammatory bowel disease, appendicitis, anal prolapse and hemorrhoid.
  • Avoid taking this product more than 10 days continuously.

 

Use during pregnancy and lactation: 
  • Avoid taking this product during pregnancy and lactation.
Product ID: 
5880555325000126
8946917614754228
Mechanism of Action: 
The therapeutic properties of senna are due to the anthraquinone glycosides (sennoside A and B). Sennosides A and B are converted into active metabolites by colon’s bacteria, as a result, they increase peristaltic contractions and fluid secretion in the colon. Furthermore, increasing the synthesis and secretion of prostaglandins, in the colon.   Histamine and 5-hydroxytryptamine in senna also have a purgative effect.  Coriander in this product decrease gastrointestinal spasms.
Active Ingredients and Components : 
+Senna (Cassia angustifolia L.), 0.46 g. +Coriander (Coriandrum sativum L.),0.007 g. ⁎Each tablet standardized based on approximately 10 mg total sennosides as sennoside B.

Side Effects:

  • Long term use and high doses of this drug cause intestinal dysfunction, diarrhea, dehydration and electrolytes loss, especially potassium.
  • High doses of senna can cause nephritis, hematuria (blood in urine) and albuminuria (protein in urine).
  • It has been observed that long term use of anthraquinone laxatives, may cause melanotic pigmentation of intestinal mucosa (melanosis coli) that will be disappear 4 months after discontinue consuming drug. 
  • Long term use of anthraquinone laxatives may cause dependence.

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