Liverofit

Liverofit

Average: 4 (9 votes)

•    Protective against hepatotoxicity, acute and chronic hepatitis & hepatic cirrhosis 
•    Prevention of inflammations, kidney damage and nephrotoxicity of antitumor drugs
•    Protection against liver toxicity of many compounds on the liver, including carbon tetrachloride, galactosamine, lanthanides, thioacetamide, butyrofenones, phenothiazines, acetaminophen, halothane, dilantin and alcohol.
•    Treatment of fatty liver disease 

Producing country: 
Iran
Pharmaceutical form: 
tablet
Indications: 
Protective against hepatotoxicity, acute and chronic hepatitis & hepatic cirrhosis
Prevention of inflammations, kidney damage and nephrotoxicity of antitumor drugs
Protection against liver toxicity of many compounds on the liver, including carbon tetrachloride, galactosamine, lanthanides, thioacetamide, butyrofenones, phenothiazines, acetaminophen, halothane, dilantin and alcohol.
Treatment of fatty liver disease
Administration and Dosage: 

Three times a day, take 1 tablet each time with a glass of water.

Technical Specifications: 

This product is made from high quality local and imported herbs organically planted and ‎harvested. It has been formulated by ‎Iran Darouk Pharmaceuticals.‎

Expiry date: 
2 Years
Drug interactions: 

Milk thistle may increase the effect of chemotherapy drugs.
Consult your physician before taking Liverofit with metronidazole, doxorubicin, yohimbine, phenothiazine such as butyrophenone, phentolamine, sugar blood lowering agents, anticoagulants such as warfarin, anti-platelets, drugs metabolized by CYP450, glucuronidated drugs (lamotrigine, haloperidol, morphine, …), P-glycoprotein substrates (digoxin, quinidine, …), raloxifen, sirolimus, tamoxifen, sulfasalazine, tacrolimus and topoisomerase I.
 

Physical characteristics: 
60 tablets in plastic container with child-proof cap in cardboard box; patient information leaflet inside.
Storage: 

Store in a dry place, below 25 °C and keep away from direct sunlight.
Keep out of sight and reach of children.

‎Disposal 
Do not put into sewer lines. Dispose in the everyday rubbish bin.‎
 

Contraindications and precautions: 

When NOT to take it 
•    Avoid taking this drug if you are allergic to the active substance or any of the other ingredients.
•    Avoid taking this drug in breast cancer patients receiving cyclophosphamide, gastric ulcer, gallstones, bile duct blockage, and allergy to Asteraceae family and also two weeks prior to an elective surgery.
•    Patients with hormone sensitive conditions, diabetes, bleeding disorders and gastroesophageal reflux should consult with a healthcare professional before use.

Side effects 
this drug may cause mild gastrointestinal problems (such as nausea, vomiting, diarrhea, constipation, dyspepsia, abdominal pain, flatulence, heartburn, abdominal fullness, loss of appetite and increasing acid secretion), polymenorrhea and allergic reactions (pruritus, urticarial, rash, eczema and anaphylaxis).
 

Use during pregnancy and lactation: 

Avoid taking this drug during pregnancy and lactation. 

Product ID: 
8984415544863810
Mechanism of Action: 
The silybin in silymarin group in this drug have strong antioxidant effects against free radicals and prevent peroxidation in liver lesions caused by toxins, chemicals and viruses. Also, silymarin prevents formation of inflammation factors, which can be beneficial in the treatment of cirrhosis or hepatic fibrosis. Effect on hepatic regeneration: Silymarin stimulates the synthesis of ribosomal proteins by increasing the activity of the enzyme RNA polymerase in the cell nucleus; this enzymatic activity increases the renewal capacity of liver cells, unlike the inhibitory effects of other toxins, like toxic mushrooms. The compounds in the extracts of turmeric have hepatic antitoxic and lipid lowering effects through mechanism effective on various kinases; they also manifest anti-inflammatory effects on the liver and other organs though inhibition of formation of inflammatory agents. Its antioxidant effects are attributed to curcumin in turmeric (Curcuma longa L.). The active ingredients in artichoke have stimulating effects on bile ducts, which result in biliary and lipid lowering effects, the combination of which help the medicinal effects of silymarin.
Active Ingredients and Components : 
Liverofit tablet is formulated and made from the extracts of milk thistle (Silybum marianum Gtn.), turmeric (Curcuma longa L.) and artichoke (Cynara scolymus L.). Liverofit tablet is made from the above three plants, in a way that 140 mg silymarin is present in every dosage form.

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